Vocabulary

5α-reductase: An enzyme required to convert testosterone to 5α-dihydrotestosterone.
Ablation: Surgical removal of brain tissue.
Action potential: A transient all-or-nothing electrical current that is conducted down the axon when the membrane potential reaches the threshold of excitation.
Affect: An emotional process; includes moods, subjective feelings, and discrete emotions.
Afferent nerves: Nerves that carry messages to the brain or spinal cord.
A-fibers: Fast-conducting sensory nerves with myelinated axons. Larger diameter and thicker myelin sheaths increases conduction speed. Aβ-fibers conduct touch signals from low-threshold mechanoreceptors with a velocity of 80 m/s and a diameter of 10 μm; Aδ-fibers have a diameter of 2.5 μm and conduct cold, noxious, and thermal signals at 12 m/s. The third and fastest conducting A-fiber is the Aα, which conducts proprioceptive information with a velocity of 120 m/s and a diameter of 20 μm.
Aggression: A form of social interaction that includes threat, attack, and fighting.
Agnosias: Due to damage of Wernicke’s area. An inability to recognize objects, words, or faces.
Agonists: A drug that increases or enhances a neurotransmitter’s effect.
Allodynia: Pain due to a stimulus that does not normally provoke pain, e.g., when a light, stroking touch feels painful.
Alogia: A reduction in the amount of speech and/or increased pausing before the initiation of speech.
Amygdala: Two almond-shaped structures located in the medial temporal lobes of the brain.
Analgesia: Pain relief.
Anhedonia: Loss of interest or pleasure in activities one previously found enjoyable or rewarding.
Anhedonia/amotivation: A reduction in the drive or ability to take the steps or engage in actions necessary to obtain the potentially positive outcome.
Antagonist: A drug that blocks a neurotransmitter’s effect.
Aphasia: Due to damage of the Broca’s area. An inability to produce or understand words.
Arcuate fasciculus: A fiber tract that connects Wernicke’s and Broca’s speech areas.
Aromatase: An enzyme that converts androgens into estrogens.
Attributional style: The tendency by which a person infers the cause or meaning of behaviors or events.
Audience design: Constructing utterances to suit the audience’s knowledge.
Autobiographical memory: Memory for the events of one’s life.
Autonomic nervous system: A part of the peripheral nervous system that connects to glands and smooth muscles. Consists of sympathetic and parasympathetic divisions.
Axial plane: See “horizontal plane.”
Axon: Part of the neuron that extends off the soma, splitting several times to connect with other neurons; main output of the neuron.
Basal ganglia: Subcortical structures of the cerebral hemispheres involved in voluntary movement.
Binocular advantage: Benefits from having two eyes as opposed to a single eye.
Blood-oxygen-level-dependent (BOLD): The signal typically measured in fMRI that results from changes in the ratio of oxygenated hemoglobin to deoxygenated hemoglobin in the blood.
Brain stem: The “trunk” of the brain comprised of the medulla, pons, midbrain, and diencephalon.
Broca’s area: An area in the frontal lobe of the left hemisphere. Implicated in language production.
Callosotomy: Surgical procedure in which the corpus callosum is severed (used to control severe epilepsy).
Case study: A thorough study of a patient (or a few patients) with naturally occurring lesions.
Catatonia: Behaviors that seem to reflect a reduction in responsiveness to the external environment. This can include holding unusual postures for long periods of time, failing to respond to verbal or motor prompts from another person, or excessive and seemingly purposeless motor activity.
Cell membrane: A bi-lipid layer of molecules that separates the cell from the surrounding extracellular fluid.
Central nervous system: The part of the nervous system that consists of the brain and spinal cord.
Central sulcus: The major fissure that divides the frontal and the parietal lobes.
Cerebellum: A nervous system structure behind and below the cerebrum. Controls motor movement coordination, balance, equilibrium, and muscle tone.
Cerebellum: The distinctive structure at the back of the brain, Latin for “small brain.”
Cerebral cortex: The outermost gray matter of the cerebrum; the distinctive convoluti characteristic of the mammalian brain.
Cerebral hemispheres: The cerebral cortex, underlying white matter, and subcortical structures.
Cerebrum: Consists of left and right hemispheres that sit at the top of the nervous system and engages in a variety of higher-order functions.
Cerebrum: Usually refers to the cerebral cortex and associated white matter, but in some texts includes the subcortical structures.
C-fibers: C-fibers: Slow-conducting unmyelinated thin sensory afferents with a diameter of 1 μm and a conduction velocity of approximately 1 m/s. C-pain fibers convey noxious, thermal, and heat signals; C-tactile fibers convey gentle touch, light stroking.
Chromosomal sex: The sex of an individual as determined by the sex chromosomes (typically XX or XY) received at the time of fertilization.
Chronic pain: Persistent or recurrent pain, beyond usual course of acute illness or injury; sometimes present without observable tissue damage or clear cause.
Chronic stress: Discrete or related problematic events and conditions which persist over time and result in prolonged activation of the biological and/or psychological stress response (e.g., unemployment, ongoing health difficulties, marital discord).
Cingulate gyrus: A medial cortical portion of the nervous tissue that is a part of the limbic system.
Common ground: Information that is shared by people who engage in a conversation.
Computerized axial tomography: A noninvasive brain-scanning procedure that uses X-ray absorption around the head.
Cones: Photoreceptors that operate in lighted environments and can encode fine visual details. There are three different kinds (S or blue, M or green and L or red) that are each sensitive to slightly different types of light. Combined, these three types of cones allow you to have color vision.
Consolidation: The process occurring after encoding that is believed to stabilize memory traces.
Contralateral: Literally “opposite side”; used to refer to the fact that the two hemispheres of the brain process sensory information and motor commands for the opposite side of the body (e.g., the left hemisphere controls the right side of the body).
Contrast: Relative difference in the amount and type of light coming from two nearby locations.
Contrast gain: Process where the sensitivity of your visual system can be tuned to be most sensitive to the levels of contrast that are most prevalent in the environment.
Converging evidence: Similar findings reported from multiple studies using different methods.
Coronal plane: A slice that runs from head to foot; brain slices in this plane are similar to slices of a loaf of bread, with the eyes being the front of the loaf.
C-pain or Aδ-fibers: C-pain fibers convey noxious, thermal, and heat signals
C-tactile fibers: C-tactile fibers convey gentle touch, light stroking
Cue overload principle: The principle stating that the more memories that are associated to a particular retrieval cue, the less effective the cue will be in prompting retrieval of any one memory.
Cutaneous senses: The senses of the skin: tactile, thermal, pruritic (itchy), painful, and pleasant.
Dark adaptation: Process that allows you to become sensitive to very small levels of light, so that you can actually see in the near-absence of light.
Defeminization: The removal of the potential for female traits.
Delusions: False beliefs that are often fixed, hard to change even in the presence of conflicting information, and often culturally influenced in their content.
Demasculinization: The removal of the potential for male traits.
Dendrite: Part of a neuron that extends away from the cell body and is the main input to the neuron.
Deoxygenated hemoglobin: Hemoglobin not carrying oxygen.
Depolarization: A change in a cell’s membrane potential, making the inside of the cell more positive and increasing the chance of an action potential.
Descending pain modulatory system: A top-down pain-modulating system able to inhibit or facilitate pain. The pathway produces analgesia by the release of endogenous opioids. Several brain structures and nuclei are part of this circuit, such as the frontal lobe areas of the anterior cingulate cortex, orbitofrontal cortex, and insular cortex; and nuclei in the amygdala and the hypothalamus, which all project to a structure in the midbrain called the periaqueductal grey (PAG). The PAG then controls ascending pain transmission from the afferent pain system indirectly through the rostral ventromedial medulla (RVM) in the brainstem, which uses ON- and OFF-cells to inhibit or facilitate nociceptive signals at the spinal dorsal horn.
Diagnostic criteria: The specific criteria used to determine whether an individual has a specific type of psychiatric disorder. Commonly used diagnostic criteria are included in the Diagnostic and Statistical Manual of Mental Disorder, 5th Edition (DSM-5) and the Internal Classification of Disorders, Version 9 (ICD-9).
Diffuse optical imaging (DOI): A neuroimaging technique that infers brain activity by measuring changes in light as it is passed through the skull and surface of the brain.
Diffusion: The force on molecules to move from areas of high concentration to areas of low concentration.
Dihydrotestosterone (DHT): A primary androgen that is an androgenic steroid product of testosterone and binds strongly to androgen receptors.
Disorganized behavior: Behavior or dress that is outside the norm for almost all subcultures. This would include odd dress, odd makeup (e.g., lipstick outlining a mouth for 1 inch), or unusual rituals (e.g., repetitive hand gestures).
Disorganized speech: Speech that is difficult to follow, either because answers do not clearly follow questions or because one sentence does not logically follow from another.
Distinctiveness: The principle that unusual events (in a context of similar events) will be recalled and recognized better than uniform (nondistinctive) events.
Dopamine: A neurotransmitter in the brain that is thought to play an important role in regulating the function of other neurotransmitters.
Early adversity: Single or multiple acute or chronic stressful events, which may be biological or psychological in nature (e.g., poverty, abuse, childhood illness or injury), occurring during childhood and resulting in a biological and/or psychological stress response.
Ectoderm: The outermost layer of a developing fetus.
Efferent nerves: Nerves that carry messages from the brain to glands and organs in the periphery.
Electroencephalography: A technique that is used to measure gross electrical activity of the brain by placing electrodes on the scalp.
Electroencephalography (EEG): A neuroimaging technique that measures electrical brain activity via multiple electrodes on the scalp.
Electrostatic pressure: The force on two ions with similar charge to repel each other; the force of two ions with opposite charge to attract to one another.
Encoding: The initial experience of perceiving and learning events.
Encoding specificity principle: The hypothesis that a retrieval cue will be effective to the extent that information encoded from the cue overlaps or matches information in the engram or memory trace.
Endocrine gland: A ductless gland from which hormones are released into the blood system in response to specific biological signals.
Endorphin: An endogenous morphine-like peptide that binds to the opioid receptors in the brain and body; synthesized in the body’s nervous system.
Engrams: A term indicating the change in the nervous system representing an event; also, memory trace.
Enzyme: A protein produced by a living organism that allows or helps a chemical reaction to occur.
Enzyme induction: Process through which a drug can enhance the production of an enzyme.
Epigenetics: Heritable changes in gene activity that are not caused by changes in the DNA sequence. http://en.wikipedia.org/wiki/Epigenetics
Episodic memory: The ability to learn and retrieve new information or episodes in one’s life.
Episodic memory: Memory for events in a particular time and place.
Estrogen: Any of the C18 class of steroid hormones, so named because of the estrus-generating properties in females. Biologically important estrogens include estradiol and estriol.
Event-related potentials: A physiological measure of large electrical change in the brain produced by sensory stimulation or motor responses.
Excitatory postsynaptic potentials: A depolarizing postsynaptic current that causes the membrane potential to become more positive and move towards the threshold of excitation.
Exteroception: The sense of the external world, of all stimulation originating from outside our own bodies.
Feminization: The induction of female traits.
Flashbulb memory: Vivid personal memories of receiving the news of some momentous (and usually emotional) event.
Flat affect: A reduction in the display of emotions through facial expressions, gestures, and speech intonation.
Forebrain: A part of the nervous system that contains the cerebral hemispheres, thalamus, and hypothalamus.
Fornix: (plural form, fornices) A nerve fiber tract that connects the hippocampus to mammillary bodies.
Frontal lobe: The front most (anterior) part of the cerebrum; anterior to the central sulcus and responsible for motor output and planning, language, judgment, and decision-making.
Frontal lobe: The most forward region (close to forehead) of the cerebral hemispheres.
Functional capacity: The ability to engage in self-care (cook, clean, bathe), work, attend school, and/or engage in social relationships.
Functional magnetic resonance imaging: (or fMRI) A noninvasive brain-imaging technique that registers changes in blood flow in the brain during a given task (also see magnetic resonance imaging).
Functional magnetic resonance imaging (fMRI): Functional magnetic resonance imaging (fMRI): A neuroimaging technique that infers brain activity by measuring changes in oxygen levels in the blood.
Globus pallidus: A nucleus of the basal ganglia.
Gonadal sex: The sex of an individual as determined by the possession of either ovaries or testes. Females have ovaries, whereas males have testes.
Grandiosity: Inflated self-esteem or an exaggerated sense of self-importance and self-worth (e.g., believing one has special powers or superior abilities).
Gray matter: Composes the bark or the cortex of the cerebrum and consists of the cell bodies of the neurons (see also white matter).
Gray matter: The outer grayish regions of the brain comprised of the neurons’ cell bodies.
Gyri: (plural) Folds between sulci in the cortex.
Gyrus: A fold between sulci in the cortex.
Gyrus: (plural form, gyri) A bulge that is raised between or among fissures of the convoluted brain.
Hallucinations: Perceptual experiences that occur even when there is no stimulus in the outside world generating the experiences. They can be auditory, visual, olfactory (smell), gustatory (taste), or somatic (touch).
Hemoglobin: The oxygen-carrying portion of a red blood cell.
Hippocampus: (plural form, hippocampi) A nucleus inside (medial) the temporal lobe implicated in learning and memory.
Homo habilis: A human ancestor, handy man, that lived two million years ago.
Homo sapiens: Modern man, the only surviving form of the genus Homo.
Horizontal plane: A slice that runs horizontally through a standing person (i.e., parallel to the floor); slices of brain in this plane divide the top and bottom parts of the brain; this plane is similar to slicing a hamburger bun.
Hormone: An organic chemical messenger released from endocrine cells that travels through the blood to interact with target cells at some distance to cause a biological response.
Hyperpolarization: A change in a cell’s membrane potential, making the inside of the cell more negative and decreasing the chance of an action potential.
Hypersomnia: Excessive daytime sleepiness, including difficulty staying awake or napping, or prolonged sleep episodes.
Hypothalamus: A brain structure located below the thalamus and above the brain stem.
Hypothalamus: Part of the diencephalon. Regulates biological drives with pituitary gland.
Immunocytochemistry: A method of staining tissue including the brain, using antibodies.
Ingroup: Group to which a person belongs.
Inhibitory postsynaptic potentials: A hyperpolarizing postsynaptic current that causes the membrane potential to become more negative and move away from the threshold of excitation.
Interoception: The sense of the physiological state of the body. Hunger, thirst, temperature, pain, and other sensations relevant to homeostasis. Visceral input such as heart rate, blood pressure, and digestive activity give rise to an experience of the body’s internal states and physiological reactions to external stimulation. This experience has been described as a representation of “the material me,” and it is hypothesized to be the foundation of subjective feelings, emotion, and self-awareness.
Invasive Procedure: A procedure that involves the skin being broken or an instrument or chemical being introduced into a body cavity.
Ion channels: Proteins that span the cell membrane, forming channels that specific ions can flow through between the intracellular and extracellular space.
Ionotropic receptor: Ion channel that opens to allow ions to permeate the cell membrane under specific conditions, such as the presence of a neurotransmitter or a specific membrane potential.
Lateral geniculate nucleus: (or LGN) A nucleus in the thalamus that is innervated by the optic nerves and sends signals to the visual cortex in the occipital lobe.
Lateral inhibition: A signal produced by a neuron aimed at suppressing the response of nearby neurons.
Lateral sulcus: The major fissure that delineates the temporal lobe below the frontal and the parietal lobes.
Lateralized: To the side; used to refer to the fact that specific functions may reside primarily in one hemisphere or the other (e.g., for the majority individuals, the left hemisphere is most responsible for language).
Lesion: A region in the brain that suffered damage through injury, disease, or medical intervention.
Lesion studies: A surgical method in which a part of the animal brain is removed to study its effects on behavior or function.
Lesions: Abnormalities in the tissue of an organism usually caused by disease or trauma.
Lexicon: Words and expressions.
Limbic system: Includes the subcortical structures of the amygdala and hippocampal formation as well as some cortical structures; responsible for aversion and gratification.
Limbic system: A loosely defined network of nuclei in the brain involved with learning and emotion.
Linguistic intergroup bias: A tendency for people to characterize positive things about their ingroup using more abstract expressions, but negative things about their outgroups using more abstract expressions.
Magnetic resonance imaging: Or MRI is a brain imaging noninvasive technique that uses magnetic energy to generate brain images (also see fMRI).
Magnetic resonance imaging: A set of techniques that uses strong magnets to measure either the structure of the brain (e.g., gray matter and white matter) or how the brain functions when a person performs cognitive tasks (e.g., working memory or episodic memory) or other types of tasks.
Magnification factor: Cortical space projected by an area of sensory input (e.g., mm of cortex per degree of visual field).
Masculinization: The induction of male traits.
Maternal behavior: Parental behavior performed by the mother or other female.
Medulla oblongata: An area just above the spinal cord that processes breathing, digestion, heart and blood vessel function, swallowing, and sneezing.
Memory traces: A term indicating the change in the nervous system representing an event.
Metabolism: Breakdown of substances.
Metabolite: A substance necessary for a living organism to maintain life.
Misinformation effect: When erroneous information occurring after an event is remembered as having been part of the original event.
Mnemonic devices: A strategy for remembering large amounts of information, usually involving imaging events occurring on a journey or with some other set of memorized cues.
Motor cortex: Region of the frontal lobe responsible for voluntary movement; the motor cortex has a contralateral representation of the human body.
Myelin: Fatty tissue, produced by glial cells (see module, “Neurons”) that insulates the axons of the neurons; myelin is necessary for normal conduction of electrical impulses among neurons.
Myelin sheath: Substance around the axon of a neuron that serves as insulation to allow the action potential to conduct rapidly toward the terminal buttons.
Neural crest: A set of primordial neurons that migrate outside the neural tube and give rise to sensory and autonomic neurons in the peripheral nervous system.
Neural induction: A process that causes the formation of the neural tube.
Neural plasticity: The ability of synapses and neural pathways to change over time and adapt to changes in neural process, behavior, or environment.
Neuroblasts: Brain progenitor cells that asymmetrically divide into other neuroblasts or nerve cells.
Neurodevelopmental: Processes that influence how the brain develops either in utero or as the child is growing up.
Neuroepithelium: The lining of the neural tube.
Neuroscience: The study of the nervous system.
Neuroscience methods: A research method that deals with the structure or function of the nervous system and brain.
Neurotransmitter: A chemical messenger that travels between neurons to provide communication. Some neurotransmitters, such as norepinephrine, can leak into the blood system and act as hormones.
Neurotransmitter: A chemical substance produced by a neuron that is used for communication between neurons.
Neurotransmitters: Chemical substance released by the presynaptic terminal button that acts on the postsynaptic cell.
Nociception: The neural process of encoding noxious stimuli, the sensory input from nociceptors. Not necessarily painful, and crucially not necessary for the experience of pain.
Nociceptors: High-threshold sensory receptors of the peripheral somatosensory nervous system that are capable of transducing and encoding noxious stimuli. Nociceptors send information about actual or impending tissue damage to the brain. These signals can often lead to pain, but nociception and pain are not the same.
Nomenclature: Naming conventions.
Noninvasive procedure: A procedure that does not require the insertion of an instrument or chemical through the skin or into a body cavity.
Noxious stimulus: A stimulus that is damaging or threatens damage to normal tissues.
Nucleus: Collection of nerve cells found in the brain which typically serve a specific function.
Nucleus accumbens: A region of the basal forebrain located in front of the preoptic region.
Occipital lobe: The back part of the cerebrum, which houses the visual areas.
Occipital lobe: The back most (posterior) part of the cerebrum; involved in vision.
Ocial touch hypothesis: Proposes that social touch is a distinct domain of touch. C-tactile afferents form a special pathway that distinguishes social touch from other types of touch by selectively firing in response to touch of social-affective relevance; thus sending affective information parallel to the discriminatory information from the Aβ-fibers. In this way, the socially relevant touch stands out from the rest as having special positive emotional value and is processed further in affect-related brain areas such as the insula.
Opponent Process Theory: Theory of color vision that assumes there are four different basic colors, organized into two pairs (red/green and blue/yellow) and proposes that colors in the world are encoded in terms of the opponency (or difference) between the colors in each pair. There is an additional black/white pair responsible for coding light contrast.
Orbital frontal cortex: A region of the frontal lobes of the brain above the eye sockets.
Outgroup: Group to which a person does not belong.
Oxygenated hemoglobin: Hemoglobin carrying oxygen.
Oxytocin: A nine amino acid mammalian neuropeptide. Oxytocin is synthesized primarily in the brain, but also in other tissues such as uterus, heart and thymus, with local effects. Oxytocin is best known as a hormone of female reproduction due to its capacity to cause uterine contractions and eject milk. Oxytocin has effects on brain tissue, but also acts throughout the body in some cases as an antioxidant or anti-inflammatory.
Oxytocin: A peptide hormone secreted by the pituitary gland to trigger lactation, as well as social bonding.
Pain: Defined as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage,” according to the International Association for the Study of Pain.
Parasympathetic nervous system: A division of the autonomic nervous system that is slower than its counterpart—that is, the sympathetic nervous system—and works in opposition to it. Generally engaged in “rest and digest” functions.
Parasympathetic nervous system (PNS): One of the two major divisions of the autonomic nervous system, responsible for stimulation of “rest and digest” activities.
Parental behavior: Behaviors performed in relation to one’s offspring that contributes directly to the survival of those offspring
Parietal lobe: An area of the cerebrum just behind the central sulcus that is engaged with somatosensory and gustatory sensation.
Parietal lobe: The part of the cerebrum between the frontal and occipital lobes; involved in bodily sensations, visual attention, and integrating the senses.
Paternal behavior: Parental behavior performed by the father or other male.
Periaqueductal gray: The gray matter in the midbrain near the cerebral aqueduct.
Peripheral nervous system: The part of the nervous system that is outside the brain and spinal cord.
Phantom pain: Pain that appears to originate in an amputated limb.
Pharmacokinetics: The action of a drug through the body, including absorption, distribution, metabolism, and excretion.
Photoactivation: A photochemical reaction that occurs when light hits photoreceptors, producing a neural signal.
Phrenology: A now-discredited field of brain study, popular in the first half of the 19th century that correlated bumps and indentations of the skull with specific functions of the brain.
Placebo effect: Effects from a treatment that are not caused by the physical properties of a treatment but by the meaning ascribed to it. These effects reflect the brain’s own activation of modulatory systems, which is triggered by positive expectation or desire for a successful treatment. Placebo analgesia is the most well-studied placebo effect and has been shown to depend, to a large degree, on opioid mechanisms. Placebo analgesia can be reversed by the pharmacological blocking of  opioid receptors. The word “placebo” is probably derived from the Latin word “placebit” (“it will please”).
Polypharmacy: The use of many medications.
Pons: A bridge that connects the cerebral cortex with the medulla, and reciprocally transfers information back and forth between the brain and the spinal cord.
Positron: A particle having the same mass and numerically equal but positive charge as an electron.
Positron Emission Tomography: (or PET) An invasive procedure that captures brain images with positron emissions from the brain after the individual has been injected with radio-labeled isotopes.
Positron emission tomography: A technique that uses radio-labelled ligands to measure the distribution of different neurotransmitter receptors in the brain or to measure how much of a certain type of neurotransmitter is released when a person is given a specific type of drug or does a particularly cognitive task.
Positron emission tomography (PET): A neuroimaging technique that measures brain activity by detecting the presence of a radioactive substance in the brain that is initially injected into the bloodstream and then pulled in by active brain tissue.
Preoptic region: A part of the anterior hypothalamus.
Primary Motor Cortex: A strip of cortex just in front of the central sulcus that is involved with motor control.
Primary Somatosensory Cortex: A strip of cerebral tissue just behind the central sulcus engaged in sensory reception of bodily sensations.
Primary visual cortex (V1): Brain region located in the occipital cortex (toward the back of the head) responsible for processing basic visual information like the detection, thickness, and orientation of simple lines, color, and small-scale motion.
Priming: A stimulus presented to a person reminds him or her about other ideas associated with the stimulus.
Processing speed: The speed with which an individual can perceive auditory or visual information and respond to it.
Progesterone: A primary progestin that is involved in pregnancy and mating behaviors.
Progestin: A class of C21 steroid hormones named for their progestational (pregnancy-supporting) effects. Progesterone is a common progestin.
Prohormone: A molecule that can act as a hormone itself or be converted into another hormone with different properties. For example, testosterone can serve as a hormone or as a prohormone for either dihydrotestosterone or estradiol.
Prolactin: A protein hormone that is highly conserved throughout the animal kingdom. It has many biological functions associated with reproduction and synergistic actions with steroid hormones.
Psychoactive drugs: A drug that changes mood or the way someone feels.
Psychomotor agitation: Increased motor activity associated with restlessness, including physical actions (e.g., fidgeting, pacing, feet tapping, handwringing).
Psychomotor retardation: A slowing of physical activities in which routine activities (e.g., eating, brushing teeth) are performed in an unusually slow manner.
Psychopathology: Illnesses or disorders that involve psychological or psychiatric symptoms.
Psychophysiological methods: Any research method in which the dependent variable is a physiological measure and the independent variable is behavioral or mental (such as memory).
Psychotropic drug: A drug that changes mood or emotion, usually used when talking about drugs prescribed for various mental conditions (depression, anxiety, schizophrenia, etc.).
Receptor: A chemical structure on the cell surface or inside of a cell that has an affinity for a specific chemical configuration of a hormone, neurotransmitter, or other compound.
Recoding: The ubiquitous process during learning of taking information in one form and converting it to another form, usually one more easily remembered.
Resting membrane potential: The voltage inside the cell relative to the voltage outside the cell while the cell is a rest (approximately -70 mV).
Retrieval: The process of accessing stored information.
Retroactive interference: The phenomenon whereby events that occur after some particular event of interest will usually cause forgetting of the original event.
Rods: Photoreceptors that are very sensitive to light and are mostly responsible for night vision.
Rostrocaudal: A front-back plane used to identify anatomical structures in the body and the brain.
Sagittal plane: A slice that runs vertically from front to back; slices of brain in this plane divide the left and right side of the brain; this plane is similar to slicing a baked potato lengthwise.
Sapir-Whorf hypothesis: The hypothesis that the language that people use determines their thoughts.
Semantic memory: The more or less permanent store of knowledge that people have.
Sensitization: Increased responsiveness of nociceptive neurons to their normal input and/or recruitment of a response to normally subthreshold inputs. Clinically, sensitization may only be inferred indirectly from phenomena such as hyperalgesia or allodynia. Sensitization can occur in the central nervous system (central sensitization) or in the periphery (peripheral sensitization).
Sex determination: The point at which an individual begins to develop as either a male or a female. In animals that have sex chromosomes, this occurs at fertilization. Females are XX and males are XY. All eggs bear X chromosomes, whereas sperm can either bear X or Y chromosomes. Thus, it is the males that determine the sex of the offspring.
Sex differentiation: The process by which individuals develop the characteristics associated with being male or female. Differential exposure to gonadal steroids during early development causes sexual differentiation of several structures including the brain.
Situation model: A mental representation of an event, object, or situation constructed at the time of comprehending a linguistic description.
Social brain hypothesis: The hypothesis that the human brain has evolved, so that humans can maintain larger ingroups.
Social networks: Networks of social relationships among individuals through which information can travel.
Social touch hypothesis: Proposes that social touch is a distinct domain of touch. C-tactile afferents form a special pathway that distinguishes social touch from other types of touch by selectively firing in response to touch of social-affective relevance; thus sending affective information parallel to the discriminatory information from the Aβ-fibers. In this way, the socially relevant touch stands out from the rest as having special positive emotional value and is processed further in affect-related brain areas such as the insula.
Social zeitgeber: Zeitgeber is German for “time giver.” Social zeitgebers are environmental cues, such as meal times and interactions with other people, that entrain biological rhythms and thus sleep-wake cycle regularity.
Socioeconomic status (SES): A person’s economic and social position based on income, education, and occupation.
Sodium-potassium pump: An ion channel that uses the neuron’s energy (adenosine triphosphate, ATP) to pump three Na+ ions outside the cell in exchange for bringing two K+ ions inside the cell.
Soma: Cell body of a neuron that contains the nucleus and genetic information, and directs protein synthesis.
Somatic nervous system: A part of the peripheral nervous system that uses cranial and spinal nerves in volitional actions.
Somatosensory (body sensations) cortex: The region of the parietal lobe responsible for bodily sensations; the somatosensory cortex has a contralateral representation of the human body.
Somatosensory cortex: Consists of primary sensory cortex (S1) in the postcentral gyrus in the parietal lobes and secondary somatosensory cortex (S2), which is defined functionally and found in the upper bank of the lateral sulcus, called the parietal operculum. Somatosensory cortex also includes parts of the insular cortex.
Somatotopically organized: When the parts of the body that are represented in a particular brain region are organized topographically according to their physical location in the body (see Figure 2 illustration).
Spatial resolution: A term that refers to how small the elements of an image are; high spatial resolution means the device or technique can resolve very small elements; in neuroscience it describes how small of a structure in the brain can be imaged.
Spatial resolution: The degree to which one can separate a single object in space from another.
Spina bifida: A developmental disease of the spinal cord, where the neural tube does not close caudally.
Spines: Protrusions on the dendrite of a neuron that form synapses with terminal buttons of the presynaptic axon.
Spinothalamic tract: Runs through the spinal cord’s lateral column up to the thalamus. C-fibers enter the dorsal horn of the spinal cord and form a synapse with a neuron that then crosses over to the lateral column and becomes part of the spinothalamic tract.
Split-brain patient: A patient who has had most or all of his or her corpus callosum severed.
Storage: The stage in the learning/memory process that bridges encoding and retrieval; the persistence of memory over time.
Stria terminalis: A band of fibers that runs along the top surface of the thalamus.
Subcortical: Structures that lie beneath the cerebral cortex, but above the brain stem.
Suicidal ideation: Recurring thoughts about suicide, including considering or planning for suicide, or preoccupation with suicide.
Sulci: (plural) Grooves separating folds of the cortex.
Sulcus: A groove separating folds of the cortex.
Sulcus: (plural form, sulci) The crevices or fissures formed by convolutions in the brain.
Sympathetic nervous system: A division of the autonomic nervous system, that is faster than its counterpart that is the parasympathetic nervous system and works in opposition to it. Generally engaged in “fight or flight” functions.
Sympathetic nervous system (SNS): One of the two major divisions of the autonomic nervous system, responsible for stimulation of “fight or flight” activities.
Synapse: Junction between the presynaptic terminal button of one neuron and the dendrite, axon, or soma of another postsynaptic neuron.
Synapse: The tiny space separating neurons.
Synaptic gap: Also known as the synaptic cleft; the small space between the presynaptic terminal button and the postsynaptic dendritic spine, axon, or soma.
Synaptic vesicles: Groups of neurotransmitters packaged together and located within the terminal button.
Synesthesia: The blending of two or more sensory experiences, or the automatic activation of a secondary (indirect) sensory experience due to certain aspects of the primary (direct) sensory stimulation.
Syntax: Rules by which words are strung together to form sentences.
Target cell: A cell that has receptors for a specific chemical messenger (hormone or neurotransmitter).
Temporal lobe: The part of the cerebrum in front of (anterior to) the occipital lobe and below the lateral fissure; involved in vision, auditory processing, memory, and integrating vision and audition.
Temporal lobe: An area of the cerebrum that lies below the lateral sulcus; it contains auditory and olfactory (smell) projection regions.
Temporal resolution: A term that refers to how small a unit of time can be measured; high temporal resolution means capable of resolving very small units of time; in neuroscience it describes how precisely in time a process can be measured in the brain.
Temporal resolution: The degree to which one can separate a single point in time from another.
Terminal button: The part of the end of the axon that form synapses with postsynaptic dendrite, axon, or soma.
Testosterone: The primary androgen secreted by the testes of most vertebrate animals, including men.
Thalamus: A part of the diencephalon that works as a gateway for incoming and outgoing information.
Thalamus: A structure in the midline of the brain located between the midbrain and the cerebral cortex.
Threshold of excitation: Specific membrane potential that the neuron must reach to initiate an action potential.
Transcranial direct current stimulation (tDCS): A neuroscience technique that passes mild electrical current directly through a brain area by placing small electrodes on the skull.
Transcranial magnetic stimulation (TMS): A neuroscience technique whereby a brief magnetic pulse is applied to the head that temporarily induces a weak electrical current that interferes with ongoing activity.
Transduction: A process in which physical energy converts into neural energy.
Transduction: The mechanisms that convert stimuli into electrical signals that can be transmitted and processed by the nervous system. Physical or chemical stimulation creates action potentials in a receptor cell in the peripheral nervous system, which is then conducted along the axon to the central nervous system.
Transverse plane: See “horizontal plane.”
Trichromacy theory: Theory that proposes that all of your color perception is fundamentally based on the combination of three (not two, not four) different color signals.
Vagus nerve: The 10th cranial nerve. The mammalian vagus has an older unmyelinated branch which originates in the dorsal motor complex and a more recently evolved, myelinated branch, with origins in the ventral vagal complex including the nucleus ambiguous. The vagus is the primary source of autonomic-parasympathetic regulation for various internal organs, including the heart, lungs and other parts of the viscera. The vagus nerve is primarily sensory (afferent), transmitting abundant visceral input to the central nervous system.
Vasopressin: A nine amino acid mammalian neuropeptide. Vasopressin is synthesized primarily in the brain, but also may be made in other tissues. Vasopressin is best known for its effects on the cardiovascular system (increasing blood pressure) and also the kidneys (causing water retention). Vasopressin has effects on brain tissue, but also acts throughout the body.
Vestibulo-ocular reflex: Coordination of motion information with visual information that allows you to maintain your gaze on an object while you move.
Visual cortex: The part of the brain that processes visual information, located in the back of the brain.
Visual hemifield: The half of visual space (what we see) on one side of fixation (where we are looking); the left hemisphere is responsible for the right visual hemifield, and the right hemisphere is responsible for the left visual hemifield.
Voltage: The difference in electric charge between two points.
Wernicke’s area: A language area in the temporal lobe where linguistic information is comprehended (Also see Broca’s area).
What pathway: Pathway of neural processing in the brain that is responsible for your ability to recognize what is around you.
Where-and-How pathway: Pathway of neural processing in the brain that is responsible for you knowing where things are in the world and how to interact with them.
White matter: Regions of the nervous system that represent the axons of the nerve cells; whitish in color because of myelination of the nerve cells.
White matter: The inner whitish regions of the cerebrum comprised of the myelinated axons of neurons in the cerebral cortex.
Working memory: The ability to maintain information over a short period of time, such as 30 seconds or less.
Working memory: Short transitory memory processed in the hippocampus.